Enantioselective Reformatsky Reaction with Ketones

doi:10.1055/s-2008-1077913

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Synfacts 2008(8): 0835-0835
DOI: 10.1055/s-2008-1077913

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

Enantioselective Reformatsky Reaction with Ketones

Contributor(s): Mark Lautens, Valentina Aureggi
M. Á. Fernández-Ibáñez, B. Maciá, A. J. Minnaard, B. L. Feringa*
University of Groningen, The Netherlands

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Publikationsdatum:
23. Juli 2008 (online)

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Significance

The development of a new catalytic system for the asymmetric Reformatsky reaction with ketones is reported. The corresponding tertiary alcohols are obtained in good yields and enantioselectivities.